Study finds distinct cellular and genetic differences in colorectal cancer in younger patients

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Researchers at Dana-Farber have reported a study examining colorectal cancer in younger patients. The work identifies cellular and genetic features that differ from those seen in older patients with the disease. The findings were published by Dana-Farber in a news release dated 2026. The source material available here is limited to the release link and a brief Hacker News listing, so further specifics such as sample sizes and clinical implications cannot be confirmed.

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Geometric Deep Learning Extends AI Beyond Flat Grids to Graphs and 3D Structures

Deep learning has long relied on flat grids, such as image pixels and text sequences, which fit CNNs and Transformers well. Many real-world systems, including molecules, social networks, protein structures, and 3D point clouds, are irregular and non-Euclidean, so forcing them into grids can discard important spatial and topological information. Geometric Deep Learning addresses this by building neural operations around mathematical symmetries and geometric transformations, using Graph Neural Networks for relational data and manifold or equivariant networks for curved and 3D spatial domains. Applications highlighted include autonomous driving perception from LiDAR point clouds and detecting multi-account money laundering in financial transaction graphs. Proponents argue the approach offers the mathematical foundation needed for AI in physical sciences and spatial computing.

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ProgrammingDEV Community ·

Running a Bilingual City Guide on Two Subdomains: Practical Lessons

Danang Plus is an independent guide to Da Nang, Vietnam, offered in Vietnamese and English on separate subdomains. The author explains that subdomains suited the project because the editions are written independently rather than machine-translated and can be deployed separately, though each must be verified and submitted to search tools on its own. Writing distinct content for each audience proved valuable, since English readers need background on matters like deposits and residence registration that locals already understand. The guide also recommends showing a "last checked" date beside volatile details such as prices and opening hours, and structuring sitemaps and canonical URLs carefully. The author concludes that writing for each readership and displaying update dates mattered more than any single technical measure.

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ProgrammingDEV Community ·

How JavaScript's using statement disposes resources after returns and exceptions

The using declaration registers an object with a disposal method and calls it when the enclosing scope ends. In a Node.js 24.15.0 test, multiple resources were disposed in reverse order of acquisition, including after an early return. Failure cases showed that if a disposal throws, remaining disposals still run and errors are chained through SuppressedError, so logging only the outer message can hide the original failure. Acquisition failures do not trigger disposal of the resource being acquired, so the acquisition function must clean up partial work itself. Asynchronous disposal with await using behaved in order, and passing a value with only asyncDispose to using without await raised a TypeError.

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ProgrammingDEV Community ·

Postman update allegedly installed plugins and a trusted hook into Claude Code and Codex

A developer reported in a GitHub issue filed on 25 October 2026 that upgrading Postman to version 12.33.4 silently installed Postman plugins into Claude Code and Codex. The reporter's installer log attributes the installs to the upgrade path itself, and their config files show a new plugin marketplace entry and a trusted record for a Postman SessionStart hook. That hook reportedly directs the agent to load Postman's API engineering skill before API tasks. The claims have not been independently reproduced publicly, and the original report does not document any sharing of API data.

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